This flavorful and moist turkey meatloaf will become your new favorite weeknight recipe! It’s an easy, healthy dinner that the whole family will love.

Moist turkey meatloaf drizzled with a tangy tomato white sauce.

It’s a new year, and despite how cliche it sounds, I am fully on the bandwagon with ditching decadent foods for a while and making meals that are light and healthy.

This recipe for Cajun turkey meatloaf has been a work-in-progress for a while. I got the inspiration from a Cajun turkey burger I had at a restaurant. It was so fresh and flavorful that I didn’t even need or want the bun (and if you know me, you know I’m not one to turn down bread).

Oven baked turkey meatloaf on a bed of arugula

The burger gave me the idea to create a turkey meatloaf recipe with the same Cajun spices, and a fresh, zesty sauce made with chopped tomatoes. I’ve never been a huge fan of the traditional ketchup-y meatloaf topping, and this sauce pairs perfectly with the turkey.

It took me some trial and error, but I finally perfected it, and I’m so excited to share it with you!

This recipe comes together quickly, so it’s completely doable on a busy weeknight. Everything gets mixed together in one bowl, formed right on the sheet pan, and tossed into the oven.

Bowl of ingredients for turkey meatloaf
Turkey meatloaf shaped into a loaf and ready to go into the oven

While it’s baking, you stir together the sauce ingredients, and you’re ready to go!

Note: Although Cajun seasonings can vary, I do not find this to be a spicy recipe. If you’re worried about spice, you can simply look for a mild Cajun seasoning, or use less of it in the recipe.

Shortcuts & Substitutions

  • If you have pre-made tartar sauce on hand, you can swap that for the mayonnaise and relish in this recipe (just use 3 tbsp total)
  • If you don’t have breadcrumbs available, you can use regular bread as a substitute. If it’s stale bread, you can grate it into breadcrumbs. If it’s fresh, use your hands to tear into small pieces.
  • If you own a food processor, you can use it to mince the vegetables quickly.
  • If you want to lighten things up even more, you can substitute low fat mayo or even greek yogurt for the regular mayo in the sauce.

What to serve with turkey meatloaf:

Since I typically make this when I want to keep things light, I like to serve it over a bed of lightly dressed greens. But if you want to make a heartier meal, this meatloaf goes great with roasted or mashed potatoes, roasted cauliflower, or rice pilaf.

Baked Cajun turkey meatloaf sliced and topped with sauce
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Servings: 8

Cajun Turkey Meatloaf

This moist and delicious turkey meatloaf is packed with flavor and topped with a unique, fresh sauce.

Ingredients

For Meatloaf

  • 1 1/2 lb lean ground turkey*
  • 1 1/2 scallions, minced
  • 1 stalk celery, minced
  • 1/4 cup roasted red peppers, minced
  • 1/4 cup fresh Italian parsley, minced
  • 1/2 cup plain breadcrumbs
  • 2 eggs, beaten
  • 1 tbsp sweet relish
  • 2 tbsp mayonnaise
  • 1 tbsp Cajun seasoning
  • 1/2 tsp kosher salt
  • 1/2 tsp pepper
  • 1 tsp Cholula or similar hot sauce

For Sauce

  • 2 roma tomatoes, diced
  • 4 tbsp mayonnaise
  • 2 tsp lime juice
  • 1/2 tsp Cajun seaoning

Instructions

  • Preheat oven to 350.
  • Add all meatloaf ingredients to a large bowl. Use hands to combine — gently, but thoroughly.
  • Line a baking sheet with nonstick foil or spray with cooking spray. Place meatloaf mixture onto the tray and shape into a loaf shape (doesn't have to be perfect).
  • Bake for approximately 40 minutes, or until internal temp reaches 160 degrees.
  • While meatloaf is baking, combine sauce ingredients in a small bowl.
  • To serve, cut meatloaf into slices and spoon the sauce over the top.

Notes

*I get the best results using 1 lb of extra lean (approx 97% lean) turkey and 1/2 lb of lean (85% lean) turkey.

Nutrition Facts

Calories 220kcal (11%)Carbohydrates 8g (3%)Protein 23g (46%)Fat 11g (17%)Saturated Fat 2g (13%)Cholesterol 92mg (31%)Sodium 416mg (18%)Potassium 372mg (11%)Fiber 1g (4%)Sugar 2g (2%)Vitamin A 889IU (18%)Vitamin C 8mg (10%)Calcium 33mg (3%)Iron 2mg (11%)
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